Advanced Stool Test
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Advanced Stool Test

This test is only available in the U.S.A. and NOT available in NY state.

The test kit will be shipped to you. Follow the directions and ship directly to the lab.

Lab results will be emailed to you.

Lab result interpretations are not provided, however consultations with Dr. Skowron's

Clinic can interpret results for you. Those appointments are an additional cost and

Available through www.NaturopathicAnswer.com

 

Spectrum Awakening Special Pricing:

List Price: $2,499

Spectrum Awakening Price: $995

 

 

The Most Comprehensive Stool Test for Optimal Clinical Utility

 

The GI Effects® Comprehensive Stool Profile is an advanced stool test that provides immediate, actionable clinical information for the management of gut health. Using the most innovative technologies available, this ground-breaking stool test offers:

    • PCR (Polymerase Chain Reaction), a molecular assay optimized for stool testing assesses 24 commensal bacteria associated in the scientific literature with health and disease, and provides valuable insight into the human microbiome

 

    • Calprotectin, an FDA-cleared biomarker that effectively differentiates between Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD)

 

    • O&P (ova & parasite), the gold standard for parasite identification

 

    • Enhanced Test Reporting that includes an Interpretation At-a-Glance overview that highlights clinically actionable biomarkers in three key areas of gut health: Infection, Inflammation, and Imbalance (Metabolic)

 

Why is this the Best Stool Test for GI Diagnostics?

Gastrointestinal function is critical for good health. Emerging evidence has associated overall GI function and gut microbiome status with a wide variety of common illnesses including, but not limited to:

  • Irritable Bowel Syndrome (IBS)
  • Inflammatory Bowel Disease (IBD)
  • Diabetes
  • Obesity
  • Cardiovascular Disease
  • Celiac and Other Malabsorption Disorders
  • Mood Disorders
  • Autoimmune
  • Autism



Clinical Overview

What is the GI Effects Comprehensive Stool Profile?

GI Effects is an innovative stool test measuring premier biomarkers of gastrointestinal function, providing valuable clinical insight into digestive performance, gut inflammation, and the gut microbiome — areas affecting not only GI health, but overall health as well.

The sophisticated biomarkers from the GI Effects Comprehensive Profile are reported using an intuitive DIG framework, providing key clinical information for three main gastrointestinal functional areas:

    • Digestion/Absorption:
      • Pancreatic Elastase-1, a marker of exocrine pancreatic function
      • Products of Protein Breakdown, markers of undigested protein reaching the colon
      • Fecal Fat, markers of fat breakdown and absorption

    • Inflammation/Immunology:
      • Calprotectin, a marker of neutrophil-driven inflammation; produced in abundance at sites of inflammation, this FDA-cleared biomarker has been proven clinically useful in differentiating between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS)
      • Eosinophil Protein X, a marker of eosinophil-driven inflammation and allergic response
      • Fecal Secretory IgA, a marker of gut secretory immunity and barrier function
      • Additional biomarkers available: Fecal Lactoferrin

    • Gut Microbiome:
      • Metabolic indicators, demonstrating specific and vital metabolic functions performed by the microbiota
        • Short-Chain Fatty Acids, a metabolomic indicator of GI microbiome health
        • Beta-glucuronidase, an inducible enzyme involved in the metabolism and bioavailability of food and drug compounds; also produced by gut bacteria

      • Commensal Bacteria, demonstrating the composition, diversity, and relative abundance of gut organisms, all of which are linked to both gastrointestinal and general health
        • More than 95% of commensal gut organisms are anaerobic and are difficult to recover by traditional (aerobic) culture techniques; molecular DNA techniques are now considered the standard for anaerobic bacteria assessment in research, permitting identification and quantification of multiple organisms with a single specimen.
        • The Polymerase Chain Reaction (PCR) methodology can identify bacterial populations at any level of taxonomy, as broadly as phylum and as narrowly as species. This ability permits analysis of the gut microbiome at a desired degree of complexity.
        • GI Effects assesses a key set of 24 clinically relevant genera/species that map to 7 major phyla.

      • Bacterial and mycological culture, which demonstrate the presence of specific beneficial and pathological organisms
        • Traditional bacterial culture complements DNA-based tests to provide an expanded survey of a patient's gut microbiota, beyond the specific organisms targeted by PCR.

      • Parasitology
        • GI Effects provides microscopic examination of fecal specimens for ova and parasites (O&P), the gold standard of diagnosis for many parasites.
        • Enzyme immunoassay (EIA), widely recognized for its diagnostic utility in the detection of pathogenic antigens, is used for the identification of Cryptosporidium, Entamoeba histolytica, and Giardia lamblia.
        • Determination of one-day or three-day sample collection is based on clinician's clinical index of suspicion for parasitic infection. If no/low suspicion, a one day sample will likely be adequate. If high suspicion, a three day sample collection is optimal.

      • Additional biomarkers available:
        • Campylobacter EIA
        • Clostridium difficile EIA
        • Escherichia coli EIA
        • Helicobacter pylori Stool Antigen EIA


Assessing and normalizing GI function can have profound effects on overall health, leading to improvement in these and other conditions. The GI Effects® Comprehensive Stool Profile is a critical clinical tool in the management of patients presenting with symptoms that can be associated with compromised gut health.

What advantage does the profile offer compared to other diagnostics?

GI Effects® represents the best technical platform to assess gut health, including an optimized PCR molecular assay for anaerobic bacteria, Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) technology for identification of cultivable species, as well as premier biomarkers for stool-based gastrointestinal diagnostics.

The test report is organized so that the clinician may move through results in a logical order that enhances clinical utility, starting with an innovative Interpretation-At-A-Glance cover page.

  • Using evidence-based rules and weighted algorithms, this page synthesizes patient test results into Four Functional Pillars of clinical significance (Infection-Inflammation-Insufficiency-Imbalance) and provides a directional indication of potential therapeutic next steps in patient management.
  • Diversity Association and Relative Abundance of gut microbiota is also reported on this page, providing both a proxy measure of gut biodiversity and the patient's levels of selected key organisms relative to similar measures in a healthy cohort of individuals.

What can clinicians and patients expect from GI Effects Comprehensive Profile stool testing?

Functional testing can help uncover the root cause of many chronic conditions that often frustrate both physician and patient. The scope of the premier biomarkers on the GI Effects Stool Profile provides comprehensive information to the clinician for the development of strategic interventions. As identified functional imbalances and inadequacies become more normalized through targeted dietary, lifestyle, and supplementation therapeutics, intractable symptoms often improve for many patients.

Each biomarker is associated with specific pertinent therapies, but general therapeutic considerations include:

  • Discerning general evidence of bowel inflammation and providing intestinal mucosal and anti-inflammatory support
  • Addressing any identified infection with appropriate pharmacological and botanical treatments
  • Supporting commensal bacteria with pre/probiotic supplements and dietary changes

A structured diagnostic panel, like the GI Effects Comprehensive Stool Profile, is easier for patients and clinicians to implement in practice compared to the stressors associated with serial testing. The GI Effects Comprehensive Stool Profile also helps to provide enhanced clinical accuracy in determining which patients may need additional, more invasive testing.

  • Item #: 21
  • Cannot ship to: Canada, United Kingdom

Advanced Stool Test

Price: $995.00
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